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Program day by day
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Time Monday May 11 11.00
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13.00Registration opens 13.00
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13.30Welcome
Bertil Romner & Pelle Johnsson13.30
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14.00Opening Lecture
Brain Damage and beyond
- Tadeusz Wieloch14.00
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14.30Invited Lecture
An overview of biochemical markers of brain damage
- Roy Sherwood14.30
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15.00Invited Lecture
From bench to bedside: the story of a new biomarker
- Diego Gazzolo15.00
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15.30Coffee 15.30
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17.00Basic Science
Chairs: Bertil Romner & Johan Undén
S100 Pathologies involving S100 proteins and RAGE.- Claus Heizmann
TAU Biomarkers for early diagnosis of neurodegenerative disorders - Oskar Hansson
GFAP & NFL Neurofilament & GFAP as possible Biochemical markers - Lars Rosengren19.00Get together at Tegnérs Time Tuesday May 12 08.15
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09.45Neurointensive care & Microdialysis
Chairs: Carl-Henrik Nordström & Urban Ungerstedt
Intracerebral microdialysis in clinical routine
- Carl-Henrik Nordström
Multimodal monitoring in the NICU: Experience from 400 microdialysis patients
- Urban Ungerstedt
Cerebral Microdialysis for Biomarker Monitoring in the Neuro-ICU
- Lars Hillered
Does increasing glutamine signal boosting metabolism in hard working astrocytes?
- Carolina Samuelsson
Clinical significance of serum S100B levels in neurointensive care
- Johan Undén09.45
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10.15Coffee
10.15
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12.00Cerebrovascular diseases
Chairs: Christian Foerch & Derk M Krieger
Astroglial proteins as biomarkers in stroke
- Christian Foerch
The future of non-invasive monitoring for ischemic brain disease
- Derk M Krieger
A multiparameter panel method for outcome prediction following aneurysmal subarachnoid hemorrhage
- Natacha Turck
Early elevation of serum GSTP and NDKA levels predict stroke events and outcome
- Natacha Turck
Explorative investigation of biomarkers of brain damage and coagulation system activation in clinical stroke differentiation.
- Gunnar Andsberg
NR2 Peptide Assay for Assessment of Cerebral Ischemic Events
- Svetlana Dambinova12.00
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13.00Lunch 13.00
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14.00Clinical chemistry
Chairs: Henrik Zetterberg & Roy Sherwood
Clinical application of neurochemical biomarkers for brain damagee
- Henrik Zetterberg
Laboratory diagnostics of brain damage
- Roy Sherwood
Neurofilament ELISA validation
- Niklas Norgren
Neurofilament Biomarkers of Brain Damage and Disease
- Gerry Shaw
Two different assays for determining S-100B in serum and urine: a comparison
- Mathias Karlsson
Comparison between capillary and venous serum S100B in traumatically head injured patients
- Ramona Åstrand14.00
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15.00Biochemical markers in Hydrocephalus
Chairs: Carsten Wikkelsö & Mats Tullberg
Do we need CSF Biomarkers for diagnosing Hydrocephalus?
- Carsten Wikkelsö
What are the diagnostic and predictive value of CSF Biomarkers in Hydrocephalus?
- Mats Tullberg15.00
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15.30Coffee 15.30
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17.00Proteomics & Genomics
Chairs: Niels Videndahl Olsen & Kevin Wang
Microarrays from research to clinic
- Finn Cilius
Geneticinfluences on outcome following acute neurological insults
- James Nicoll
Proteomic-based discovery of novel brain injury biomarkers and their validation using animal models
- Kevin Wang
Blood Pressure Response to Anesthesia: A Retrospective Analysis of the Impact of Genetic Polymorphism in the Renin-Angiotensin System, Adrenergic System and Nitric Oxide System
- Morten Nielsen
From cerebrospinal fluids to brain microdialysates: discovery of brain damage markers through quantitative proteomics
- Dayon Loïc
Risk of aneurysmal subarachnoid hemorrhage and genetic polymorphism in the nitric oxide synthase system
- Jonatan Myrup19.00Pub evening Time Wednesday May 13 08.15
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09.45Minor head injury
Chairs: Johan Undén & Bertil Romner
Initial management of mild head injury. What´s the problem?
- Johan Undén
S-100 as a routine parameter for patients suffering form MHT:
Prognostoc value, elimination kinetik and connection to postconcussion syndroms
- Peter Biberthaler
Rapid release of AMPA receptor (AMPAR) peptide correlates with concussion and mild traumatic brain injury (TBI)
- Svetlana Dambinova
Evaluation of serum S100B sampling in clinical head injury management
- Olga Calcagnile
09.45
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10.15Coffee 10.15
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11.00Minor head injury
Chairs: Kay Müller & Will Townend
S100B serum level predicts computed tomography findings after minor head injury
- Kay Müller
Biomarkers in initial assessment head injury: a role in decision rules?
- Will Townend
Serum S100B in mild traumatic brain injury
- Morochovi Radoslav
Prediction of time trends in recovery of cognitive function after mild head injury
- Kay Mûller11.00
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12.00Biochemical markers in Sport injuries
Chairs: Nicola Biasca & Kai Blennow
Minor traumatic brain injury in sports: a review in order to prevent neurological sequelae.
- Nicola Biasca
Biochemical markers in Sport Injuries
- Kai Blennow12.00
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13.00Lunch 13.00
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15.00Severe head injury
Chairs: Bo-Michael Bellander & Lars-Ove Koskinen
Challenges of TBI biomarker assay development and validation in human severe TBI study
- Kevin Wang
ApoE-epsilon4 allele influences the levels of S-100B and NSE in severe head injury
- Lars-Ove Koskinen
Neuron specific enolase and protein S100B as markers for brain damage after traumatic brain injury (TBI)
- Marjan Korsic
Does extracerebral trauma affect the predictive values of S100B regarding cerebral injuries?
- Søren Ohrt-Nissen
Temporal profiles in serum concentrations of S100B after traumatic brain injury inflict on outcome
- Bo-Michael Bellander15.00
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15.30Coffee 15.30
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17.00Pediatric issues
Chairs: Rachel Berger & Vineta Fellman
Searching for the Holy Grail: Biomarkers in Pediatric TBI
- Rachel Berger
Hypothermia treatment for the asphyxiated newborn infant
- Vineta Fellman
Role of targeted quantitative Metabolomics in biomarker discovery of perinatal brain injury
- David Enot
Serum and urine S-100B after traumatic head injury in children
- Magnus Hallén
Age and gender distribution of capillary and venous serum S100B among healthy children
- Ramona Åstrand
19.00Banquet Time Thursday May 14 08.15
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09.45Neuroprotection/ Hypothermia
Chairs: Hans Friberg & Tadeusz Wieloch
- Hans Friberg
Molecular mechanisms of hypothermic protection
- Tadeusz Wieloch
NSE predicts poor neurological outcome in hypothermia treated cardiac arrest
- Malin Rundgren
S100B values after subarachnoid hemorrage with intravenous vs oral nimodipine
-JK Länsberg09.45
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10.15Coffee 10.15
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11.00Brain imaging 2009
Chairs: Olaf B Paulson & Bertil Romner
Brain imaging - what can we expect in the coming decade?
- Olaf B Paulson
Imaging macro- and microstructural brain changes following severe head injury
- Annette Sidaros11.00
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12.00Future Aspects
- Kevin Wang
- Tor Ingebrigtsen
- Roy Sherwood
- Rachel Berger12.00
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13.0013.00-13.00
Conclusion and farewell
- Bertil Romner
- Johan Undén
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