3rd International Hypothermia Symposium

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Scientific program


Time	Wednesday September 2, 2009
12.00 - 14.00	Registration
14.00 - 14.15	Welcome Hans Friberg & Tadeusz Wieloch
14.15 - 15.00	Key note lecture Patrick Kochanek
Traumatic Brain and Spinal Cord Injury Chairs: B Romner, P Kochanek
15.00 - 15.20	Early Induction of Hypothermia in Severe Brain Injury Guy Clifton
15.20 - 15.50	Coffee and Exhibits
15.50 - 16.10	Managing hypothermia: side effects & practical aspects Kees Polderman
16.10 - 16.30	Effects of therapeutic mild hypothermia on the cerebral hemisphere pressure gradient Wusi Qiu
16.30 - 16.50	Therapeutic mild hypothermia for severe traumatic brain injury in Japan. Results of the RCT Tsuyoshi Maekawa
16.50 - 17.05	How to move forward – The Eurotherm Study Peter Andrews
17.05 - 18.00	Short communications and Discussion Long-term hypothermia using H2S acts neuroprotectively in aged rats after focal ischemia Aurel Popa-Wagner Fever After Severe TBI: Good or Bad for Outcome? Views from a UK Consensus Meeting Charmaine Childs Selective Brain Cooling Attenuated Neruophysiological Dysfunction Induced by Penetrating Ballistic-like Brain Injury in Rats May Lu The impact of mild controlled hypothermia on an occurrence of extracranial inflammatory complications in the patients after severe head injury Mrlian Andrej
18.00 -	Buffet dinner at the venue


Time	Thursday September 3, 2009
Physiology of Hypothermia Chairs: P-O Grände, G Clifton
08.00 - 08.15	Blood gases and hypothermia Rainer Kollmar
08.15 - 08.30	Hemostasis, bleeding and hypothermia Oscar Braun
08.30 - 08.45	Immunology and hypothermia Ulrich Dirnagl
08.45 - 09.00	Drugs and hypothermia Patrick Kochanek
09.00 - 09.20	Discussion
09.20 - 09.50	Coffee and Exhibits
Neonatal Encephalopathy Chairs: M Thoresen, S Shankaran
09.50 - 10.10	Xenon-hypothermia treating global hypoxic-ischemic injury in long term surviving newborn models Marianne Thoresen
10.10 - 10.30	The Mechanisms of Perinatal Brain Injury: overview and effect of hypothermia Henrik Hagberg
10.30 - 10.50	Hypothermia as Neuroprotection for Neonatal Hypoxic-ischemic encephalopathy Seetha Shankaran
10.50 - 12.00	Short communications and Discussion Effect of hypothermia, timing and sedation on cardiac Troponin I after global hypoxica-ischemia (HIE) with brain injury in newborn pigs Xun Liu Cerebral Oximetry Using Near-Infrared Spectroscopy in Infants Undergoing Hypothermic Cardiopulmonary Bypass for the Surgical Correction of Acyanotic Heart Disease Reilly Hobbs Methylprednisolone and deep hypothermia are neuroprotective after NMDA induced cell injury in neonatal mouse brain slices Katharina Schmitt Moderate Hypothermia Suppresses Superoxide Radical Generation in the Jugular Vein and HMGB1 in Brain and Plasma in the Forebrain Ischemia-Reperfusion Rat Motoki Fujita
12.00 - 13.00	Lunch
Cardiac Arrest Chairs: F Sterz and H Friberg
13.00 - 13.20	Hypothermia as Therapy in Brain Ischemia after Cardiac Arrest Fritz Sterz
13.20 - 13.40	How to cool and when – a try for optimisation Nicolas Deye
13.40 - 14.00	Intracranial pressure and cerebral metabolism during therapeutic hypothermia Sten Rubertsson
14.00 - 14.20	Therapeutic hypothermia after cardiac arrest – not only for VF arrests Kjetil Sunde
14.20 - 14.40	The International Cardiac Arrest Registry (INTCAR) Niklas Nielsen
14.40 - 15.30	Short communications and Discussion “COOL IT”: Therapeutic hypothermia as a new standard of care in treating transfer patients following out-of-hospital cardiac arrest Mooney Michael Time to target temperature with mild therapeutic hypothermia in patients after cardiac arrest Fritz Sterz New method of intra-arrest trans-nasal cooling in Stockholm - The PRINCE II study Per Nordberg Endovascular Cooling is Not Faster than Surface Cooling in Post-Arrest Patients Jon Rittenberger
15.30 - 16.00	Coffee and Exhibits
Prognostication of coma after cardiac arrest Chairs: T Cronberg and M Oddo
16.00 - 16.20	SSEP, NSE and preliminary results from the PROPAC II study Janneke Horn
16.20 - 16.40	Neuromonitoring of patients with brain anoxia in the era of hypothermia: the role of continuous EEG Mauro Oddo
16.40 - 17.00	Prediction of outcome after cardiac arrest and induced hypothermia – a multimodal strategy Tobias Cronberg
17.00 - 18.00	Short communications and Discussion Early electrophysiologic markers of post-resuscitation functional outcome with therapeutic hypothermia Xiaofeng Jia Revaluating prognosis after mild therapeutic hypothermia in unconscious victims of cardiac arrest Tommaso Pellis Blood cell biosignatures in patients after cardiac arrest treated with hypothermia Pascal Stammet Intracerebral microdialysis in patients with post-cardiac arrest brain injury with therapeutic hypothermia Yasuhiro Kuroda
19.00 –	Traditional Crayfish Party with Hats Kulturen


Time	Friday September 4, 2009
Cardiac Ischemia and Resuscitation Chairs: P Johnsson and KB Kern
08.30 – 09.50	Resuscitation after Cardiac Arrest – the effect of hypothermia and mechanical compressions Stig Steen
08.50 – 09.10	Myocardial infarction and therapeutic hypothermia David Erlinge
09.10 – 09.30	Urgent invasive coronary strategy and hypothermia in comatose survivors of cardiac arrest Marko Noc
09.30 – 10.00	Coffee and Exhibits
10.00 – 10.20	Post cardiac arrest myocardial function and the effect of hypothermia Karl B Kern
10.20 – 11.20	Short communications and Discussion Mild Hypothermia Markedly Reduces Ischemia Related Coronary t-PA Release Jesper van der Pals Cardiovascular effects of milrinone during rewarming from hypothermia in an intact animal model Erik Sveberg Dietrichs Hypothermia to limit myocardial infarct size in awake patients with Acute ST-elevation Myocardial Infarction (STEMI) - the CAMARO trial Kees Polderman Rapid cooling in the cathlab with a combination of cold saline and endovascular catheter for patients with ST-elevation myocardial infarction Matthias Götberg
11.20 - 12.20	Lunch
Mechanisms of Hypothermia Tissue protection Chair: T Wieloch and D Dietrich
12.20 – 12.40	Molecular mechanisms underlying cognitive dysfunction after TBI: Effects of modest hypothermia Dalton Dietrich
12.40 – 13.00	Use of systemic and focal hypothermia in rodent models of intracerebral hemorrhage and ischemia Fredrick Colbourne
13.00 – 13.20	Molecular mechanisms of hypothermia protection Guo-yi Gao
13.20 – 13.40	Molecular and Cellular Mechanisms of Mild and Moderate Hypothermic Protection after Focal Ischemia Gary Steinberg
13.40 – 14.00	Cellular and subcellular motility - targets for therapeutic hypothermia Tadeusz Wieloch
14.00 – 14.30	Coffee and Exhibits
14.30 – 15.30	Short communications and Discussion Influence of mild hypothermia on pro- and anti-inflammatory cytokines after a transient focal cerebral ischemia in rats An-Gaëlle Ceulemans Hypothermia after cardiopulmonary resuscitation attenuates brain pro-inflammatory cytokine mRNA expression Patrick Meybohm Optimisation of the therapeutic window of post-ischemic mild hypothermia in the endothelin-1 rat model for transient focal cerebral ischemia Tine Zgavc
New devices and chemical hypothermia Chair: D Erlinge and K Polderman
15.40 – 15.55	Extracorporeal cooling Michael Wanscher
15.55 – 16.10	Prostaglandin E2 in temperature regulation Anders Blomqvist
16.10 – 16.25	Cooling down with hot chilli and cannabis Edward Högestätt
16.25 – 16.40	Neurotensin and Hibernaid, medications to induce regulated hypothermia and optimize therapeutic hypothermia Laurence Katz
16.40 - 16.55	Adenosine receptors and body temperature Bertil Fredholm
16.55 - 17.45	Short communications and Discussions Development of a pharyngeal cooling system that enables brain temperature to be immediately reduced Yoshimasa Takeda Theoretical evaluations of therapeutic systemic and local cerebral hypothermia Emanuela Keller Automatic Control System of Brain Temperature by Water Surface Cooling for Clinical Application Tomohiko Utsuki
19.30 –	Gala Dinner at The Grand Hotel


Time	Saturday September 5, 2009
Stroke and Neurointensive Care Chair: B Norrving, P Lyden
09.00 – 09.20	Management and pitfalls of hypothermia treatment Nariyuki Hayashi
09.20 – 09.40	Measurement and management of shivering Stephan Mayer
09.40 – 10.00	Hypothermia in malignant stroke Eric Jütter
10.00 - 10.30	Coffee and Exhibits
10.30 – 10.50	Hypothermia for stroke; Results of the ICTuS-L Trial Patrick Lyden
10.50 – 11.10	EuroCools. Hypothermia for stroke – application and clinical practice Jesper Petersson
11.10 – 12.00	Short communications and Discussion Treatment of hypopituitarism in severe brain damage: an unrecognized fundament for successful therapeutic hypothermia Cicero Coimbra Body temperature at 24 hours rather than on admission is related to functional outcome after stroke H. Bart van der Worp High-dose paracetamol reduces systolic blood pressure in acute stroke H. Bart van der Worp
12.00 – 13.00	Panel discussion and Closing remarks. The Hayashi Prize for the best abstract. Presentation of the 2011 Conference Venue. Adjourn. Luncbox.

Scientific program