Chemometrics epistemology in System Biology

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Scientific program

Preliminary program


Time	May 9 (Monday)
09.30	Ornithology in Falsterbo (Optional)	Registration
12.00	Lunch at Norregård (Conference Site)
	SESSION 1: Analytical quality and data management Chair: Jenny Forshed
13.00	Data quality and data validity in ‘omics based biomarker discovery *Prof. Jonas Bergqvist* (Uppsala University, Sweden)
14.00	Omics Study Design as a Key to Valid Research Findings *Ass. Prof. Juergen von Frese* (Data Analysis Solutions, Greifenberg, Germany)
15.00	Coffee at Norregård (Conference Site)
15.30	Discussions Moderator: Ingrid Pettersson
16.30	Linking protein expression data with interactome data – a strategy for predicting endocrine resistance in breast cancer patients treated with tamoxifen L. Hultin-Rosenberg (Karolinska Institute, Sweden) An evaluation approach for the quantitative label-free LC-MS workflow *Marianne Sandin* (Lund University, Sweden) Eicosanoid profiling reveals shunting towards pgd2 pathway in mpges1 knock-out mice *Helena Idborg* (Karolinska Institute, Sweden)
18.00	Wings Over Falsterbo
19.00	Dinner at Norregård (Conference Site)


Time	May 10 (Tuesday)
	SESSION 2: Information from data: Chemometrics principles and methods Chair: Lars Munck
09.00	Univariate, simplivariate and multivariate analysis of metabolomics data *Prof. Age Smilde* (Biosystems Data Analysis,University of Amsterdam, Netherlands)
10.00	Coffee at Norregård (Conference Site)
10.15	Data integration, time series analysis and model interpretation of multivariate data *Ass. Prof. Johan Trygg* (Computational life science cluster (CLiC), Umeå University, Sweden)
11.15	Discussions Moderator: Jürgen von Frese
12.00	Lunch at Norregård (Conference Site)
	SESSION 3: Information from data – Applications Chair: Johan Trygg
13.00	Systems Biology linking experiments with previous knowledge and theory *Prof. Mark Stitt* (Director of Max Planck Institute of Molecular Plant Physiology, Golm, Germany) Presentation
14.00	Modelling time series in metabolomics using uni- and multivariate approaches *Dr. Tim Ebbels* (Biomolecular Medicine, Department of Surgery and Cancer, Imperial College London)
15.00	Coffee at Norregård (Conference Site)
15.30	Discussions
16.30	A Strategy for Optimizing UPLC-MS Data-Processing Parameters – a DoE approach *Mattias Eliasson* (Umeå Uneversity, Sweden) Membrane proteomics analysis of adrenocortical tumors identifies a down-regulation of the tumor suppressor protein GRIM-19 in the malignant tissue compared to benign *Hanna Eriksson* (Karolinska Institute, Sweden) Quantitative Proteome Profiling of Human Papilloma Virus influence on Vulvar Carcinoma on a global and individual tumour level *AnnSofi Sandberg* (SciLife Lab Stockholm and Karolinska Institute, Sweden) The deterministic irreducibility of data from the biological individual modifies the epistemological strategy for chemometrics in system biology *Lars Munck* (Life science faculty University of Copenhagen, Denmark)
19.00	Dinner at Rögeriet in Skanör harbour


Time	May 11 (Wednsday)
	SESSION 4: Knowledge management Chair: J. Gottfries
09.00	Knowledge hyphenation and inter disciplinary communication *Dr. Nicholas Waters* (Neurosearch, Göteborg, Sweden)
10.00	Coffee at Norregård (Conference Site)
10.15	Institutionalizing technoscience: Post-genomic technologies and the case of systems biology *Dr. Mats Sundgren* (AstraZeneca R&D, Mölndal, Sweden) Presentation
11.15	Discussions Moderator: Peder Svensson
12.00	Lunch at Norregård (Conference Site)
	Tomorrows challenges
13.00	Panel discussion
15.00	Coffee at Norregård (Conference Site)